2P005 Crystal structure of heme binding protein P46 from Bacteroides fragilis
نویسندگان
چکیده
منابع مشابه
Crystal Structure of a new Transcarbamylase from the Anaerobic Bacterium Bacteroides fragilis at 2.0 Å Resolution
No. shi25 Crystal Structure of a new Transcarbamylase from the Anaerobic Bacterium Bacteroides fragilis at 2.0 Å Resolution D. Shi (CNMC), R. Gallegos, J. DePonte III (Tufts U.), H. Morizono, X. Yu (CNMC), N.M ALLewell (UMD), M. Malamy (Tufts U.) and M. Tuchman (CNMC) Beamline(s): X12C Introduction: In the course of characterizing the arginine biosynthetic genes in Bacteroides fragilis (B. frag...
متن کاملCrystal structure of the wide-spectrum binuclear zinc beta-lactamase from Bacteroides fragilis.
BACKGROUND The metallo-beta-lactamase from Bacteroides fragilis hydrolyzes a wide range of beta-lactam antibiotics, and is not clinically susceptible to any known beta-lactamase inhibitors. B. fragilis is associated with post-surgery hospital infections, and there has been a recent report of plasmid-mediated dissemination of the enzyme. Effective inhibitors are therefore urgently needed. Knowle...
متن کاملIdentification of the alpha-enolase P46 in the extracellular membrane vesicles of Bacteroides fragilis
BACKGROUND Members of the Bacteroides fragilis group are the most important components of the normal human gut microbiome, but are also major opportunistic pathogens that are responsible for significant mortality, especially in the case of bacteraemia and other severe infections, such as intra-abdominal abscesses. Up to now, several virulence factors have been described that might explain the i...
متن کاملCrystal structure of hemoglobin protease, a heme binding autotransporter protein from pathogenic Escherichia coli.
The acquisition of iron is essential for the survival of pathogenic bacteria, which have consequently evolved a wide variety of uptake systems to extract iron and heme from host proteins such as hemoglobin. Hemoglobin protease (Hbp) was discovered as a factor involved in the symbiosis of pathogenic Escherichia coli and Bacteroides fragilis, which cause intra-abdominal abscesses. Released from E...
متن کاملNutritional features of Bacteroides fragilis subsp. fragilis.
Studies of three reference strains of Bacteroides fragilis subsp. fragilis showed that they grow well in a minimal defined medium containing glucose, hemin, vitamin B(12), minerals, bicarbonate-carbon dioxide buffer, NH(4)Cl, and sulfide. The vitamin B(12) requirement of 0.1 ng/ml was replaced with 7.5 mug of methionine. Cysteine or sulfide was an excellent source of sulfur, thioglycolate was a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 2004
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.44.s111_1